Many years ago, on an Earth of an alternate dimension, there lived a man named Dr. Michael Grant. Grant was a scientist who had developed an experimental chemical agent known as Cortexin. He tested his mutagenic drug on several species of animals inside of his laboratory including, apes, rats, bats and tigers. The exact purpose or nature of the Cortexin compound remains shrouded in mystery however.

Shortly after beginning the initial stages of his experiments, the world fell sway to a global catastrophe commonly referred to as the Great Disaster. Earthquakes and tidal waves erupted all across the globe and the nations of Earth found themselves at the mercy of nuclear Armageddon. Dr. Grant did not survive long enough to see his experiments come to fruition, but the lasting after-effects produced a legacy that would endure for centuries.

A large section of the Earth was rendered uninhabitable due to atmospheric nuclear radiation. However, the radiation produced a mutagenic side-effect with the surviving Cortexin-infected animals from Dr. Grant's labs. Not only were they safe from the long-term side-effects of nuclear fallout, but the strange drug permanently altered their genetic structure. With each successive generation, the various animal species began to evolve adopting specific physical human characteristics. Within two human generations, apes, birds, felines, canines and many other breeds were developing heightened intellect, bipedal locomotion, extra fingers, toes, thumbs and even the ability to articulate.

As each race grew in strength and numbers, they began to form primitive tribal societies and family clans. Many of the clans did not live in harmony with their cousins, and a culture of survival of the fittest soon developed among them.

History

Centuries after the Great Disaster, the species known as the Tiger-Men became one of the most powerful and growing clans of all the animal races. They established what would become known as the Tiger Empire - a domain that covered most of the Eastern seaboard of the former United States. Leading the empire was the Great Caesar, a proud yet overbearing tyrant who despised the sparse human population. He learned of an intelligent human named Kamandi, as well as his three mutant friends, Ben Boxer, Steve and Renzi. Caesar dedicated himself towards Kamandi’s destruction and made secret dealings with a Serpent-Man named Sacker to hunt him down and kill him. Ultimately the Great Caesar’s goals were never realized, and Kamandi evaded (or escaped) capture at every turn.

Final Crisis

During Final Crisis, The Evil factory created a team of Tiger-Men to suit Kalibak's new body and ferocity. They rode on canine mounts like the rest of Darkseid's army and wore green tunics. One of them was a white furred tiger-man, while another wore a headband simalar to of Tuftan's. they watch Kalibak's fight with Tawky Tawny, refusing to help him when he was fatally wounded because of the belief that only the strong should live. They soon accept Tawny as the leader of their pack.