Patrick Wayne is the father of Thomas Wayne and grandfather to Bruce Wayne. He is the eldest son of Kenneth and Elizabeth Wayne. His father developed Wayne Chemical, but died at a fairly young age leaving the fortune to his 37-year-old wife Laura Wayne. Laura was a shrewd businesswoman and heavily involved in the Prohibition movement, while raising their infant son. Patrick inherited the family business upon his mother's death. He was the creator of Wayne Tech which helped support both World Wars. Later, he would combine the Wayne resources to create Wayne Corp. He worked closely with his brother Silas Wayne.

He had built The Odissey ship holding great pieces of art from the Nazis and sending to America to be safe. Unafortunatedly the ship sunked at open sea losing all. Patrick Wayne felt responsible that it was lost while in his care so he financed yearly salvage expeditions which Wayne Enterprises continues to this day.